李满玉 发表于 2015-12-16 22:53:21

凡德 不可治疗肺癌

本帖最后由 李满玉 于 2015-12-16 23:05 编辑

1.        http://www.ncbi.nlm.nih.gov/pubmed/22370318
这片文章显示凡德不仅无用, 副作用还大, 不可用与治疗肺癌.
CONCLUSION:
The study did not demonstrate an overall survival benefit for vandetanib versus placebo. There was a higher incidence of some adverse events with vandetanib.
2.        https://en.wikipedia.org/wiki/Vandetanib
Clinical trials
Non-small cell lung cancer
The drug underwent clinical trials as a potential targeted treatment for non-small-cell lung cancer. There have been some promising results from a phase III trial with docetaxel. There have also been ambivalent results when used with pemetrexed. Another trial with docetaxel was recruiting in July 2009.
AstraZeneca withdrew EU regulatory submissions for vandetanib (under the proposed trade name Zactima) in October 2009 after trials showed no benefit when the drug was administered alongside chemotherapy.
阿斯利康已经于2009 年十月撤消了临床试验. 它和安慰剂没有任何治疗的统计差异,也就是无任何作用, 除了一些副作用. 因此大家应该慎重考虑. 我观察到网友也基本是无作用或作用不大的反应.

sunzongbao2007 发表于 2015-12-18 08:50:26

恩？ 那就是不用准备凡德他尼了么？

pingpinger21 发表于 2015-12-19 15:39:16

我看好多病友都吃过

18952090760 发表于 2015-12-20 15:27:25

我吃的，反应很大，吃2片降压药血压都下不来，赶紧停药

sqxyz 发表于 2015-12-20 16:31:11

论坛里有部分人吃了是有效的呀，抑制E靶点和V靶点

春野 发表于 2015-12-20 20:56:09

我曾服凡德24天，副作用很大，CT肺部进展，停服

李满玉 发表于 2015-12-21 20:41:41

个人觉得还是应该相信用凡德做过临床试验的药厂, 有用的话为什么不继续? 病友有反映有效的, 但是进一步看用凡德期间CEA基本无降低, 或无明显降低.

LOVEME 发表于 2015-12-21 21:58:50

谢谢分享信息！

APPLE 发表于 2015-12-21 22:32:09

获得最新信息，感谢楼主！

Yunxiao 发表于 2015-12-23 06:43:35

我家刚吃上特，想着按憨叔的方法，下一步要换凡德呢，现在这样，我该换什么呢？好纠结
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